Journal article

`Pre-prosthetic use of poly(lactic-co-glycolic acid) membranes treated with oxygen plasma and TiO2 nanocomposite particles for guided bone regeneration processes'

Gabriel Castillo-Dali, Raquel Castillo-Oyaguee, Antonia Terriza, Jean-Louis Saffar, Antonio Batista-Cruzado, Christopher D Lynch, Alastair J Sloan, Jose-Luis Gutierrez-Perez, Daniel Torres-Lagares

Journal of Dentistry | ELSEVIER SCI LTD | Published : 2016

Abstract

OBJECTIVES: Guided bone regeneration (GBR) processes are frequently necessary to achieve appropriate substrates before the restoration of edentulous areas. This study aimed to evaluate the bone regeneration reliability of a new poly-lactic-co-glycolic acid (PLGA) membrane after treatment with oxygen plasma (PO2) and titanium dioxide (TiO2) composite nanoparticles. METHODS: Circumferential bone defects (diameter: 10mm; depth: 3mm) were created on the parietal bones of eight experimentation rabbits and were randomly covered with control membranes (Group 1: PLGA) or experimental membranes (Group 2: PLGA/PO2/TiO2). The animals were euthanized two months afterwards, and a morphologic study was th..

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