Dental pulp stem cells: what, where, how?
Alastair J Sloan, Rachel J Waddington
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY | WILEY | Published : 2009
INTRODUCTION: It is now accepted that progenitor/stem cells reside within the post-natal dental pulp. Studies have identified several niches of multipotent mesenchymal progenitor cells, known as dental pulp stem cells, which have a high proliferative potential for self-renewal. These progenitor stem cells are now recognized as being vital to the dentine regeneration process following injury. Understanding the nature of these progenitor/stem cell populations in the pulp is important in determining their potentialities and development of isolation or recruitment strategies for use in regeneration and tissue engineering. Characterization of these cells, and determination of their potentialities..View full abstract