Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

X Liu; Q Dai; R Ye; W Zi; Y Liu; H Wang; W Zhu; M Ma; Q Yin; M Li; X Fan; W Sun; Y Han; Q Lv; R Liu; D Yang; Z Shi; D Zheng; X Deng; Y Wan; Z Wang; Y Geng; X Chen; Z Zhou; G Liao; P Jin; Y Liu; X Liu; M Zhang; F Zhou; H Shi; Y Zhang; F Guo; C Yin; G Niu; M Zhang; X Cai; Q Zhu; Z Chen; Y Liang; B Li; M Lin; W Wang; H Xu; X Fu; W Liu; X Tian; Z Gong; H Shi; C Wang; P Lv; Z Tao; L Zhu; S Yang; W Hu; P Jiang; DS Liebeskind; VM Pereira; T Leung; B Yan; S Davis; G Xu; RG Nogueira; Y Xiong; Z Shi; W Zheng; X Huang; Y Liu; H Li; K Ke; S Yang; H Lin; W Dan; L Chen; L Rong; S Wang; J Fan; C Xing; H Li; W Yang; C Wang; Y Zhang; X Li; D Liebeskind

Journal article

Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

X Liu, Q Dai, R Ye, W Zi, Y Liu, H Wang, W Zhu, M Ma, Q Yin, M Li, X Fan, W Sun, Y Han, Q Lv, R Liu, D Yang, Z Shi, D Zheng, X Deng, Y Wan Show all

Lancet Neurology | Published : 2020

DOI: 10.1016/S1474-4422(19)30395-3

Abstract

Background: Previous randomised trials have shown an overwhelming benefit of mechanical thrombectomy for treating patients with stroke caused by large vessel occlusion of the anterior circulation. Whether endovascular treatment is beneficial for vertebrobasilar artery occlusion remains unknown. In this study, we aimed to investigate the safety and efficacy of endovascular treatment of acute strokes due to vertebrobasilar artery occlusion. Methods: We did a multicentre, randomised, open-label trial, with blinded outcome assessment of thrombectomy in patients presenting within 8 h of vertebrobasilar occlusion at 28 centres in China. Patients were randomly assigned (1:1) to endovascular therapy..

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