Journal article

Arteria: An automation system for a sequencing core facility

Johan Dahlberg, Johan Hermansson, Steinar Sturlaugsson, Mariya Lysenkova, Patrik Smeds, Claes Ladenvall, Roman Valls Guimera, Florian Reisinger, Oliver Hofmann, Pontus Larsson

GigaScience | OXFORD UNIV PRESS | Published : 2019

Abstract

BACKGROUND: In recent years, nucleotide sequencing has become increasingly instrumental in both research and clinical settings. This has led to an explosive growth in sequencing data produced worldwide. As the amount of data increases, so does the need for automated solutions for data processing and analysis. The concept of workflows has gained favour in the bioinformatics community, but there is little in the scientific literature describing end-to-end automation systems. Arteria is an automation system that aims at providing a solution to the data-related operational challenges that face sequencing core facilities. FINDINGS: Arteria is built on existing open source technologies, with a mod..

View full abstract

University of Melbourne Researchers

Grants

Awarded by Australian Genomics Health Alliance - National Health andMedical Research Council


Awarded by Akademiska University Hospital


Funding Acknowledgements

This work was supported by the R&D group at the SNP&SEQ Technology Platform in Uppsala. This facility is part of the National Genomics Infrastructure (NGI) Sweden and Science for Life Laboratory. The SNP&SEQ Platform is also supported by the Swedish Research Council and the Knut and Alice Wallenberg Foundation. UMCCR work was funded through the Australian Genomics Health Alliance, which is supported by the National Health andMedical Research Council (GNT1113531). Clinical Genomics Uppsala is part of the Diagnostics Development platform within Science for Life Laboratory. Work at the Clinical Genomics Uppsala facility was also supported by grants from the Akademiska University Hospital (ALF-717721).