Journal article
Propagation-Based Phase-Contrast CT of the Breast Demonstrates Higher Quality Than Conventional Absorption-Based CT Even at Lower Radiation Dose
S Tavakoli Taba, BD Arhatari, YI Nesterets, Z Gadomkar, SC Mayo, D Thompson, J Fox, B Kumar, Z Prodanovic, D Hausermann, A Maksimenko, C Hall, M Dimmock, KM Pavlov, D Lockie, M Gity, A Peele, HM Quiney, S Lewis, TE Gureyev Show all
Academic Radiology | ELSEVIER SCIENCE INC | Published : 2021
Abstract
Rationale and Objectives: Propagation-based phase-contrast CT (PB-CT) is an advanced X-ray imaging technology that exploits both refraction and absorption of the transmitted X-ray beam. This study was aimed at optimizing the experimental conditions of PB-CT for breast cancer imaging and examined its performance relative to conventional absorption-based CT (AB-CT) in terms of image quality and radiation dose. Materials and Methods: Surgically excised breast mastectomy specimens (n = 12) were scanned using both PB-CT and AB-CT techniques under varying imaging conditions. To evaluate the radiological image quality, visual grading characteristics (VGC) analysis was used in which 11 breast specia..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by National Health and Medical Research Council (NHMRC), Australia [grant number APP1138283].