Propagation-Based Phase-Contrast CT of the Breast Demonstrates Higher Quality Than Conventional Absorption-Based CT Even at Lower Radiation Dose
Seyedamir Tavakoli Taba, Benedicta D Arhatari, Yakov I Nesterets, Ziba Gadomkar, Sheridan C Mayo, Darren Thompson, Jane Fox, Beena Kumar, Zdenka Prodanovic, Daniel Hausermann, Anton Maksimenko, Christopher Hall, Matthew Dimmock, Konstantin M Pavlov, Darren Lockie, Masoumeh Gity, Andrew Peele, Harry M Quiney, Sarah Lewis, Timur E Gureyev Show all
Academic Radiology | ELSEVIER SCIENCE INC | Published : 2021
RATIONALE AND OBJECTIVES: Propagation-based phase-contrast CT (PB-CT) is an advanced X-ray imaging technology that exploits both refraction and absorption of the transmitted X-ray beam. This study was aimed at optimizing the experimental conditions of PB-CT for breast cancer imaging and examined its performance relative to conventional absorption-based CT (AB-CT) in terms of image quality and radiation dose. MATERIALS AND METHODS: Surgically excised breast mastectomy specimens (n = 12) were scanned using both PB-CT and AB-CT techniques under varying imaging conditions. To evaluate the radiological image quality, visual grading characteristics (VGC) analysis was used in which 11 breast specia..View full abstract
Awarded by National Health and Medical Research Council (NHMRC), Australia
This work was supported by National Health and Medical Research Council (NHMRC), Australia [grant number APP1138283].