The clinical profile of NMOSD in Australia and New Zealand
Wajih Bukhari, Laura Clarke, Cullen O'Gorman, Elham Khalilidehkordi, Simon Arnett, Kerri M Prain, Mark Woodhall, Roger Silvestrini, Christine S Bundell, Sudarshini Ramanathan, David Abernethy, Sandeep Bhuta, Stefan Blum, Mike Boggild, Karyn Boundy, Bruce J Brew, Wallace Brownlee, Helmut Butzkueven, William M Carroll, Celia Chen Show all
JOURNAL OF NEUROLOGY | SPRINGER HEIDELBERG | Published : 2020
Neuromyelitis optica spectrum disorders (NMOSD) are an inflammation of the central nervous system associated with autoantibodies to aquaporin-4. We have undertaken a clinic-based survey of NMOSD in the Australia and New Zealand populations with the aim of characterising the clinical features and establishing the value of recently revised diagnostic criteria. Cases of possible NMOSD and age and sex-matched controls with multiple sclerosis (MS) were referred from centres across Australia and New Zealand. Cases were classified as NMOSD if they met the 2015 IPND criteria and remained as suspected NMOSD if they did not. Clinical and paraclinical data were compared across the three groups. NMOSD w..View full abstract
Awarded by Multiple Sclerosis Research Australia
Funding for this project was provided by Multiple Sclerosis Research Australia (Project Grant 11-038), Brain Foundation, Griffith Univerrsity/Gold Coast Hospital Foundation, Contributing to Australian Scholarship and Science, and NHS National Specialised Commissioning Group for NMO, NIHR Oxford Biomedical Research centre.