Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M-1 Muscarinic Acetylcholine Receptor with Weak Agonist Activity and Diverse Modulatory Profiles
Juliana CC Dallagnol, Elham Khajehali, Emma T van der Westhuizen, Manuela Jorg, Celine Valant, Alan G Goncalves, Ben Capuano, Arthur Christopoulos, Peter J Scammells
Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2018
Awarded by Australian Research Council
Awarded by National Health and Medicinal Research Council (NHMRC) of Australia
This research was supported by Discovery Grant DP110100687 of the Australian Research Council as well as Program Grant APP1055134 of the National Health and Medicinal Research Council (NHMRC) of Australia. A.C. is a Senior Principal Research Fellow of the NHMRC. J.C.C.D. thanks the CNPq (National Council for Scientific and Technological Development of Brazil) for a scholarship.