Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M-1 Muscarinic Acetylcholine Receptors

Emma T van der Westhuizen; Arthur Spathis; Elham Khajehali; Manuela Jorg; Shailesh N Mistry; Ben Capuano; Andrew B Tobin; Patrick M Sexton; Peter J Scammells; Celine Valant; Arthur Christopoulos

Journal article

Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M-1 Muscarinic Acetylcholine Receptors

Emma T van der Westhuizen, Arthur Spathis, Elham Khajehali, Manuela Jorg, Shailesh N Mistry, Ben Capuano, Andrew B Tobin, Patrick M Sexton, Peter J Scammells, Celine Valant, Arthur Christopoulos

Molecular Pharmacology | AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS | Published : 2018

DOI: 10.1124/mol.118.111633

University of Melbourne Researchers

Elham Khajehali Author Anatomy and Physiology

Grants

Awarded by National Health and Medical Research Council Program

Funding Acknowledgements

This work was supported by National Health and Medical Research Council Program Grant [APP1055134]. A.C. is a senior principal and P.M.S. a principal research fellow of the National Health and Medical Research Council of Australia. C.V. is supported by a Future Fellowship from the Australian Research Council. E.T.v.d.W. is supported by an Early Career Fellowship from the National Health and Medical Research Council of Australia.