Journal article

Increased ankle muscle coactivation in the early stages of multiple sclerosis.

L Eduardo Cofré Lizama, Andisheh Bastani, Anneke van der Walt, Trevor Kilpatrick, Fary Khan, Mary P Galea

Multiple Sclerosis Journal - Experimental, Translational and Clinical | SAGE Publications | Published : 2020


Background: Neural damage at early stages of multiple sclerosis (MS) can subtly affect gait muscle activation patterns. Detecting these changes using current clinical tools, however, is not possible. We propose using muscle coactivation measures to detect these subtle gait changes. This may also help in identifying people with MS (PwMS) that may benefit from strategies aimed at preventing further mobility impairments. Objective: We aimed to determine if coactivation of ankle muscles during gait is greater in PwMS with Expanded Disability Status Scale (EDSS) score <3.5. A secondary aim is to determine whether coactivation increases are speed dependent. Methods: For this study 30 PwMS and 15 h..

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