Journal article

The Value of Twins for Health and Medical Research: A Third of a Century of Progress

Jeffrey M Craig, Lucas Calais-Ferreira, Mark P Umstad, Dedra Buchwald

TWIN RESEARCH AND HUMAN GENETICS | CAMBRIDGE UNIV PRESS | Published : 2020

Abstract

In 1984, Hrubec and Robinette published what was arguably the first review of the role of twins in medical research. The authors acknowledged a growing distinction between two categories of twin studies: those aimed at assessing genetic contributions to disease and those aimed at assessing environmental contributions while controlling for genetic variation. They concluded with a brief section on recently founded twin registries that had begun to provide unprecedented access to twins for medical research. Here we offer an overview of the twin research that, in our estimation, best represents the field has progress since 1984. We start by summarizing what we know about twinning. We then focus ..

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Grants

Awarded by Australian National Health and Medical Research Council


Awarded by Financial Markets Foundation For Children


Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

The authors thank Raymond M. Harris, PhD, for his invaluable reviews of the manuscript. JMC is supported by grants from the Australian National Health and Medical Research Council (grant numbers 1011070 and 1083779), the Financial Markets Foundation For Children (grant number 032-2007) and the Murdoch Children's Research Institute, which is funded by the Victorian Government's Operational Infrastructure Support Program. LCF and JMC are supported by a Centre of Research Excellence Grant (1079102) from the National Health and Medical Research Council of Australia. LCF is supported by Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES), Ministry of Education, Brazil.