Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study.
Barbara Goeggel Simonetti, Mubeen F Rafay, Melissa Chung, Warren D Lo, Lauren A Beslow, Lori L Billinghurst, Christine K Fox, Alberto Pagnamenta, Maja Steinlin, Mark T Mackay, undefined IPSS Study Group
Neurology | Published : 2020
OBJECTIVE: To compare risk factors, clinical presentation, and outcomes after posterior circulation arterial ischemic stroke (PCAIS) and anterior circulation arterial ischemic stroke (ACAIS) in neonates and children. METHODS: In this international multicenter observational study including neonates and children up to 18 years of age with arterial ischemic stroke (AIS), we compared clinical and radiologic features according to stroke location. RESULTS: Of 2,768 AIS cases, 507 (18%) were located in the posterior circulation, 1,931 (70%) in the anterior circulation, and 330 (12%) involved both. PCAIS was less frequent in neonates compared to children (8.8% vs 22%, p < 0.001). Children with PCAIS..View full abstract