Journal article

The time window of pet ownership exposure modifies the relationship of Environmental Tobacco Smoke with lung function: A large population-based cohort study

Li-Wen Hu, Shu Yu, Tia Marks, Yun-Ting Zhang, Caroline C Lodge, Shyamali C Dharmage, Namratha Gurram, Michael S Bloom, Shao Lin, Mohammed Zeeshan, Hong-Yao Yu, Yang Zhou, Ru-Qing Liu, Bo-Yi Yang, Xiao-Wen Zeng, Qiang Hu, Guang-Hui Dong

ENVIRONMENTAL RESEARCH | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2020

Abstract

There is a large body of evidence linking Environmental Tobacco Smoke (ETS) exposure with impaired lung function. However, it is not known whether exposure to pets modifies this relationship. To investigate if pet ownership changes the association between ETS exposure and lung function, a population-based sample of 7326 children, 7-14 years old, were randomly recruited from 24 districts in northeast China. Lung function including forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), peak expiratory flow (PEF), and maximal mid-expiratory flow (MMEF) was measured by spirometry, while pet ownership time periods and ETS exposure were collected by questionnaire. Two-level regressio..

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Grants

Awarded by National Natural Science Foundation of China


Awarded by Science and Technology Program of Guangzhou


Awarded by National Key Research and Development Program of China


Awarded by Fundamental Research Funds for the Central Universities


Awarded by Natural Science Foundation of Guangdong Province


Funding Acknowledgements

This work was supported by the National Natural Science Foundation of China (81673128, 81872582, 81872583, 81673127, 81001255), the Science and Technology Program of Guangzhou (201807010032, 201803010054), National Key Research and Development Program of China (2018YFE0106900, 2018YFC1004300), Fundamental Research Funds for the Central Universities (19ykjc01, 17ykpy14, 17ykpy16), and Natural Science Foundation of Guangdong Province (2019A050510017, 2018B030312005, 2018B05052007, 2017A090905042, 2016A030313342).