Journal article

Effects of FABP4 variation on milk fatty-acid composition for dairy cattle grazed on pasture in late lactation

Yunhai Li, Huitong Zhou, Long Cheng, Miriam Hodge, Jenny Zhao, Rosy Tung, Grant Edwards, Jonathan Hickford

Journal of Dairy Research | CAMBRIDGE UNIV PRESS | Published : 2020


This research communication describes associations between variation in the fatty acid binding protein 4 gene (FABP4) and milk fat composition in New Zealand Holstein-Friesian × Jersey cross dairy cows. After correcting for the effect of the amino acid substitution p.K232A in diacylglycerol O-acyltransferase 1 (DGAT1), which is associated with variation in many milk fatty acid (FA) component levels, the effect of FABP4 c.328A/G on milk FA levels was typically small. For the five genotypes analysed, the AB cows produced more medium-chain fatty acids than CC cows (P < 0.05), and more C14:0 FA than AA and AC cows (P < 0.05). The AA and AC cows produced less C22:0 FA (P < 0.01) than the BC cows,..

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University of Melbourne Researchers


Awarded by Ministry of Science and Innovation (Dairy Systems for Environmental Protection; NZ)

Funding Acknowledgements

Financial support from the Ministry of Science and Innovation (DRCX 0802; Dairy Systems for Environmental Protection; NZ) and Lincoln University Gene-Marker Laboratory are acknowledged. We thank Helen Hague from Lincoln University for sampling. We also thank the manager and staff of LUDF for their supports.