Journal article

Taxonomic and functional assessment using metatranscriptomics reveals the effect of Angus cattle on rumen microbial signatures

ALA Neves, Y Chen, K-A Le Cao, S Mandal, TJ Sharpton, T McAllister, LL Guan

ANIMAL | ELSEVIER | Published : 2020


A greater understanding of the rumen microbiota and its function may help find new strategies to improve feed efficiency in cattle. This study aimed to investigate whether the cattle breed affects specific ruminal taxonomic microbial groups and functions associated with feed conversion ratio (FCR), using two genetically related Angus breeds as a model. Total RNA was extracted from 24 rumen content samples collected from purebred Black and Red Angus bulls fed the same forage diet and then subjected to metatranscriptomic analysis. Multivariate discriminant analysis (sparse partial least square discriminant analysis (sPLS-DA)) and analysis of composition of microbiomes were conducted to identif..

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University of Melbourne Researchers


Awarded by Alberta Livestock and Meat Agency

Awarded by Alberta Agriculture and Forestry

Awarded by National Health and Medical Research Council (NHMRC) Career Development fellowship

Funding Acknowledgements

This project was supported by Alberta Livestock and Meat Agency (2013R029R) and Alberta Agriculture and Forestry (2018F095R) as well as the NSERC Discovery Grant. KALC was supported in part by the National Health and Medical Research Council (NHMRC) Career Development fellowship (GNT1087415). The authors also acknowledge the Brazilian Agricultural Research Corporation (EMBRAPA) and the Alberta Innovates Technology Futures (AITF) for providing Ph.D. scholarships, as well as Dr. Kim Ominski (University of Manitoba, Canada) for providing the rumen samples used in this study. We would like to thank Mr. Cameron Olson for his advice on the beef cattle production aspects in North America.