Journal article

Estimation of the force of infection and infectious period of skin sores in remote Australian communities using interval-censored data

Michael J Lydeamore, Patricia T Campbell, David J Price, Yue Wu, Adrian J Marcato, Will Cuningham, Jonathan R Carapetis, Ross M Andrews, Malcolm I McDonald, Jodie McVernon, Steven YC Tong, James M McCaw

Cold Spring Harbor Laboratory

Abstract

Prevalence of impetigo (skin sores) remains high in remote Australian Aboriginal communities, Fiji, and other areas of socio-economic disadvantage. Skin sore infections, driven primarily in these settings by Group AStreptococcus(GAS) contribute substantially to the disease burden in these areas. Despite this, estimates for the force of infection, infectious period and basic reproductive ratio — all necessary for the construction of dynamic transmission models — have not been obtained. By utilising three datasets each containing longitudinal infection information on individuals, we estimate each of these epidemiologically important parameters. With an eye to future study design, we also quant..

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University of Melbourne Researchers

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