Journal article

Clinical characteristics and outcomes of invasive Lomentospora prolificans infections: Analysis of patients in the FungiScope (R) registry

Jeffrey D Jenks, Danila Seidel, Oliver A Cornely, Sharon Chen, Sebastiaan van Hal, Carol Kauffman, Marisa H Miceli, Melina Heinemann, Martin Christner, Alfredo Jover Saenz, Alexander Burchardt, Bjoern Kemmerling, Raoul Herbrecht, Joerg Steinmann, Shmuel Shoham, Sandra Graeber, Livio Pagano, Dries Deeren, Monica A Slavin, Martin Hoenigl

Mycoses | WILEY | Published : 2020

Abstract

OBJECTIVES: Invasive fungal infections caused by Lomentospora prolificans are associated with very high mortality rates and can be challenging to treat given pan-drug resistance to available antifungal agents. The objective of this study was to describe the clinical presentation and outcomes in a cohort of patients with invasive L prolificans infections. METHODS: We performed a retrospective review of medical records of patients with invasive L prolificans infection in the FungiScope® registry of rare invasive fungal infections. Patients diagnosed between 01 January 2008 and 09 September 2019 were included in for analysis. RESULTS: The analysis included 41 patients with invasive L prolifican..

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