Journal article

Physical health trajectories of young people commenced on clozapine

B O'Donoghue, A Mujanovic, S Young, T Bridson, L Mora, M Bismark, J Cocks, D Siskind, P McGorry

IRISH JOURNAL OF PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2021

Abstract

OBJECTIVES: Clozapine is the most effective antipsychotic medication, but it has the highest propensity for metabolic side effects. A clozapine clinic was established within an early intervention for psychosis service to facilitate the timely commencement of clozapine and to manage the associated adverse effects. This study describes the changes in the weight, body mass index (BMI), waist circumference and blood pressure after 6 months in young people commenced on clozapine. METHOD: This was a prospective cohort study of all young people, aged 15-24 years, commenced on clozapine within an early intervention service in Melbourne, Australia, between 01.04.2016 and 30.06.2018. Continuous data w..

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