The role of Thallium-201 scintigraphy and Tc-99m pentavalent dimercaptosuccinic acid in diagnosis and grading of chondrosarcoma
Olivia Jo, Stephen Schlicht, John Slavin, Claudia Di Bella, Grant Pang, Gerard Powell, Tim Spelman, Peter FM Choong
European Journal of Radiology | ELSEVIER IRELAND LTD | Published : 2020
PURPOSE: Distinguishing between enchondromas and low-grade (grade 1) chondrosarcomas can be challenging. The aim of this study was to investigate the role of Thallium-201 scintigraphy and Technetium-99 m pentavalent dimercaptosuccinic acid (Tc-99 m DMSA (V)) in the diagnosis and grading of chondrosarcomas. METHODS: 232 consecutive patients with pathologically proven cartilaginous tumours between the years 2000 and 2018 were evaluated. We included 197 patients (101 males and 96 females; median age 50 years; range 15-86 years) who underwent Thallium-201(n = 193) and/or Tc-99 m DMSA (V) scanning (n = 67). Increased uptake was defined as uptake greater than background. The reference standard was..View full abstract
This study has not received any funding. However, we declare that one of the authors has received institutional research grants from Johnson & Johnson P/L and MEdacta AB, and is a member of the Surgeon Advisory Board for Oncology for Stryker Corporation.