Journal article

Modes of late mortality in patients with a Fontan circulation

Chin Poh, Tim Hornung, David S Celermajer, Dorothy J Radford, Robert N Justo, David Andrews, Karin du Plessis, Ajay J Iyengar, David Winlaw, Yves d'Udekem

Heart | BMJ PUBLISHING GROUP | Published : 2020

Abstract

OBJECTIVES: The mechanisms of attrition of the Fontan population have been poorly characterised and it is unclear whether some of the deaths are potentially preventable. We analysed the circumstances of late death in patients with a Fontan circulation, with a special focus on identifying lesions amenable to intervention that may have contributed to the decline of their circulation. METHODS: Between 1975 and 2018, a total of 105 patients from a Bi-National Registry died beyond 1 year after Fontan completion, at a median age of 18.6 (IQR 13.8-26.0) years old, 12.7 (IQR 6.0-19.3) years after Fontan completion. RESULTS: A total of 105 patients died-63 patients (60%) with an atriopulmonary (AP) F..

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