Journal article

Haemodynamic effect of a 20% albumin fluid bolus in post-cardiac surgery patients

Salvatore L Cutuli, Laurent Bitker, Eduardo A Osawa, Zachary O'Brien, Emmanuel Canet, Fumitaka Yanase, Paolo Ancona, Anthony Wilson, Luca Lucchetta, Mark Kubicki, Maria Cronhjort, Luca Cioccari, Lea Peck, Helen Young, Glenn M Eastwood, Johan Martensson, Neil J Glassford, Rinaldo Bellomo

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine | AUSTRALASIAN MED PUBL CO LTD | Published : 2020

Abstract

OBJECTIVE: To study the cardiovascular effect over 30 minutes following the end of fluid bolus therapy (FBT) with 20% albumin in patients after cardiac surgery. DESIGN: Prospective observational study. SETTING: Intensive care unit of a tertiary university-affiliated hospital. PARTICIPANTS: Twenty post-cardiac surgery mechanically ventilated patients with a clinical decision to administer FBT. INTERVENTION: FBT with a 100 mL bolus of 20% albumin. MAIN OUTCOME MEASURES: Cardiac index (CI) response was defined by a ≥ 15% increase, while mean arterial pressure (MAP) response was defined by a ≥ 10% increase. RESULTS: The most common indication for FBT was hypotension (40%). Median duration of inf..

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