Sodium bicarbonate in 5% dextrose: can clinicians tell the difference?
Briony Jude, Thummaporn Naorungroj, Ary Serpa Neto, Tomoko Fujii, Andrew Udy, Rinaldo Bellomo
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine | Published : 2020
BACKGROUND: Due to the lack of double-blind randomised controlled trials, the true effect of intravenous sodium bicarbonate therapy in ICU patients with metabolic acidosis remains unclear. METHODS: We diluted 100 mL 8.4% sodium bicarbonate in 150 mL 5% dextrose (D5W) within a 250 mL polyolefin bag after removing 100 mL. We asked ICU clinicians to inspect a 250 mL bag containing sodium bicarbonate or a 250 mL bag where 100 mL of D5W had been removed and then returned. The bags were attached to intravenous giving sets. We asked participants to identify the contents of the bags. RESULTS: Among 60 participants (39 nursing staff [65%], 20 medical staff [33.3%] and one pharmacist), 36 (60%) answer..View full abstract