Circuit Survival during Continuous Venovenous Hemodialysis versus Continuous Venovenous Hemofiltration
Alfonso Maria Califano, Laurent Bitker, Ian Baldwin, Nigel Fealy, Rinaldo Bellomo
Blood Purification | KARGER | Published : 2020
BACKGROUND: Continuous renal replacement therapy (CRRT) technique may affect circuit lifespan. A shorter circuit life may reduce CRRT efficacy and increase costs. METHODS: In a before-and-after study, we compared circuit median survival time during continuous venovenous hemofiltration (CVVH) versus continuous venovenous hemodialysis (-CVVHD). We performed log-rank mixed effects univariate analysis and Cox mixed effect regression modeling to define predictors of circuit lifespan. RESULTS: We compared 197 -CVVHD and 97 CVVH circuits in 39 patients. There was no overall difference in circuit lifespan. When no anticoagulation was used, median circuit survival time was shorter for CVVH circuits (..View full abstract
A.M.C. thanks the Spanish Society of Nephrology and the Department of Nephrology of Hospital del Mar, Barcelona, Spain, for their support during his stay at Austin Hospital.