Journal article

Adaptation to Industrial Stressors Through Genomic and Transcriptional Plasticity in a Bioethanol Producing Fission Yeast Isolate

Dane Vassiliadis, Koon Ho Wong, Jo Blinco, Geoff Dumsday, Alex Andrianopoulos, Brendon Monahan



Schizosaccharomyces pombe is a model unicellular eukaryote with ties to the basic research, oenology and industrial biotechnology sectors. While most investigations into S. pombe cell biology utilize Leupold's 972h - laboratory strain background, recent studies have described a wealth of genetic and phenotypic diversity within wild populations of S. pombe including stress resistance phenotypes which may be of interest to industry. Here we describe the genomic and transcriptomic characterization of Wilmar-P, an S. pombe isolate used for bioethanol production from sugarcane molasses at industrial scale. Novel sequences present in Wilmar-P but not in the laboratory S. pombe genome included mult..

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Awarded by Faculty of Health Sciences of the University of Macau

Awarded by Research Services and Knowledge Transfer Office of the University of Macau

Funding Acknowledgements

We thank Wilmar Ltd. Mackay, Queensland, Australia, for provision of the Wilmar strains for analysis, knowledge exchange regarding the history of the Wilmar isolate, and funding for whole genome and RNA-sequencing experiments detailed herein. We also thank Tom Peat for administrative assistance throughout the study. Koon Ho Wong is supported by funds from Faculty of Health Sciences and Research Services and Knowledge Transfer Office (MYRG2016-00211-FHS) of the University of Macau.