Journal article
Profile of and risk factors for poststroke cognitive impairment in diverse ethnoregional groups
Jessica W Lo, John D Crawford, David W Desmond, Olivier Godefroy, Hanna Jokinen, Simin Mahinrad, Hee-Joon Bae, Jae-Sung Lim, Sebastian Kohler, Elles Douven, Julie Staals, Christopher Chen, Xin Xu, Eddie J Chong, Rufus O Akinyemi, Rajesh N Kalaria, Adesola Ogunniyi, Melanie Barbay, Martine Roussel, Byung-Chul Lee Show all
NEUROLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2019
Abstract
OBJECTIVE: To address the variability in prevalence estimates and inconsistencies in potential risk factors for poststroke cognitive impairment (PSCI) using a standardized approach and individual participant data (IPD) from international cohorts in the Stroke and Cognition Consortium (STROKOG) consortium. METHODS: We harmonized data from 13 studies based in 8 countries. Neuropsychological test scores 2 to 6 months after stroke or TIA and appropriate normative data were used to calculate standardized cognitive domain scores. Domain-specific impairment was based on percentile cutoffs from normative groups, and associations between domain scores and risk factors were examined with 1-stage IPD m..
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Awarded by MRC
Funding Acknowledgements
This work was supported by the Vincent Fairfax Family Foundation (Australia) and the National Health and Medical Research Council of Australia Program Grant. Funding information for individual studies is available from Dryad (appendix T20, doi.org/10.5061/dryad.m517990).