Pediatric ASPECTS predicts outcomes following acute symptomatic neonatal arterial stroke
Mark T Mackay, Nedelina Slavova, Manuela Pastore-Wapp, Sebastian Grunt, Belinda Stojanovski, Susan Donath, Maja Steinlin
NEUROLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2020
OBJECTIVE: To test the hypothesis that the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is useful in determining outcomes after neonatal arterial ischemic stroke (NAIS), we assessed accuracy of the modified pediatric ASPECTS (pedASPECTS) to predict cerebral palsy (CP), neurologic impairment, and epilepsy. METHODS: Cross-sectional study included newborns with acute NAIS whose outcomes were assessed at ≥18 months after stroke. PedASPECTS accuracy to predict outcomes was determined by sensitivity, specificity, and receiver operator characteristic (ROC) curves, and correlation between pedASPECTS and infarct volume was determined by the Spearman correlation coefficient. RESULT..View full abstract
M. Mackay received grant funding from the Cerebral Palsy Alliance.