Journal article

Implantable cardioverter-defibrillators and patient-reported outcomes in adults with congenital heart disease: An international study

Valerie Levesque, Laurence Laplante, Azadeh Shohoudi, Silke Apers, Adrienne H Kovacs, Koen Luyckx, Corina Thomet, Werner Budts, Junko Enomoto, Maayke A Sluman, Chun-Wei Lu, Jamie L Jackson, Stephen C Cook, Shanthi Chidambarathanu, Luis Alday, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Andrew S Mackie Show all



BACKGROUND: Implantable cardioverter-defibrillators (ICDs) are increasingly being used to prevent sudden death in the growing population of adults with congenital heart disease (CHD). However, little is known about their impact on patient-reported outcomes (PROs). OBJECTIVE: The purpose of this study was to assess and compare PROs in adults with CHD with and without ICDs. METHODS: A propensity-based matching weight analysis was conducted to evaluate PROs in an international cross-sectional study of adults with CHD from 15 countries across 5 continents. RESULTS: A total of 3188 patients were included: 107 with ICDs and 3081 weight-matched controls without ICDs. ICD recipients were an average ..

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Awarded by Research Fund-KU Leuven (Leuven, Belgium) Grant

Awarded by Swedish Heart-Lung Foundation

Awarded by Cardiac Children's Foundation (Taiwan)

Funding Acknowledgements

This work was supported by the Research Fund-KU Leuven (Leuven, Belgium) Grant OT/11/033; Swedish Heart-Lung Foundation Grant 20130607; University of Gothenburg Centre for Person-centred Care; and Cardiac Children's Foundation (Taiwan) Grant CCF2013_02.