Journal article

Presentation and outcome of patients with intracranial tuberculoma in a high HIV prevalence setting

S Marais, I Roos, A Mitha, V Patel, T Kalincik, A Bhigjee

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | Published : 2020

Abstract

SETTING: A referral hospital in South Africa.OBJECTIVE: To describe the clinical presentation, serial brain imaging findings during treatment and outcome of patients with intracranial tuberculoma in a high human immunodeficiency virus (HIV) prevalence setting.DESIGN: This was a retrospective observational study conducted over a 12.5-year period. Records of adults (age ≥18 years) who presented with neurological TB were screened. We included patients with tuberculoma in whom sequential brain imaging was performed.RESULTS: Of 66 patients enrolled, HIV status was known in 61; 47 (71%) were HIV-infected and 14 (21%) were non-HIV-infected. Clinical and imaging findings and outcomes were similar be..

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