Journal article

Recommendations for the Prescription of Opioids at Discharge After Abdominopelvic Surgery: A Systematic Review

David DQ Zhang, Fahima Dossa, Anuj Arora, Maria C Cusimano, Brittany Speller, Tari Little, Karim Ladha, Savtaj Brar, David R Urbach, Andrea C Tricco, Duminda N Wijeysundera, Hance A Clarke, Nancy N Baxter



Importance: The prescription of opioids at discharge after abdominopelvic surgery is variable and often excessive. A lack of guidance for abdominopelvic surgeons may explain the suboptimal nature of current prescribing practices. Objective: To systematically review existing recommendations on the prescription of opioids at discharge, the appropriate disposal of opioids, and the prevention of chronic postsurgical opioid use after abdominopelvic surgery. Evidence Review: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. From January 2010 to December 2018, a search of MEDLINE, PsycINFO, HealthSTAR, Embase, and the difficu..

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Awarded by CIHR Operating Grant

Funding Acknowledgements

This study was funded by a CIHR Operating Grant (OCK 156784). Drs Ladha and Clarke are supported in part by Merit Awards from the Department of Anesthesia at the University of Toronto. Dr Tricco is supported by a Tier 2 Canada Research Chair in Knowledge Synthesis.Dr Wijeysundera is supported in part by a New Investigator Award from the CIHR, an Excellence in Research Award from the Department of Anesthesia at the University of Toronto, and the Endowed Chair in Translational Anesthesiology Research at St Michael's Hospital and University of Toronto.