Journal article

The Effect of Electric Cross-Talk in Retinal Neurostimulation

Paul B Matteucci, Alejandro Barriga-Rivera, Calvin D Eiber, Nigel H Lovell, John W Morley, Gregg J Suaning

Investigative Opthalmology & Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2016

Abstract

PURPOSE: To investigate the efficacy of electric field shaping in modulating the extent and activation threshold in retinal neurostimulation. This study aims to quantify the interference of neighboring stimulation sites by assessing the shift in the activation threshold produced by a concomitant interfering stimulus. METHODS: Electrical stimuli were applied to healthy retinae in a feline model (n = 4) using a 24-channel electrode array surgically implanted in the suprachoroidal space. A 96-channel penetrating electrode array was used for recording cortical responses to a number of stimulation paradigms. Data were analyzed offline. Concurrent monopolar and hexapolar stimuli were delivered at ..

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