Repurposing a fracture risk calculator (FRAX) as a screening tool for women at risk for sarcopenia
JA Pasco, M Mohebbi, MC Tembo, KL Holloway-Kew, NK Hyde, LJ Williams, MA Kotowicz
OSTEOPOROSIS INTERNATIONAL | SPRINGER LONDON LTD | Published : 2020
Osteoporosis and sarcopenia share risk profiles, so we tested a fracture risk assessment tool (FRAX) as a screening tool for sarcopenia. FRAX probabilities without bone mineral density predicted sarcopenia with high sensitivity and reasonable specificity. There is potential to use this FRAX as a screening tool for sarcopenia. PURPOSE: There is a need for simple screening tools for sarcopenia. As osteoporosis and sarcopenia share risk profiles, we tested the performance of a fracture risk assessment tool for discriminating individuals at risk for sarcopenia. METHODS: In this longitudinal study, FRAX (Australia) probabilities were calculated for 354 women (ages 40-90 years) in the Geelong Oste..View full abstract
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Awarded by National Health and Medical Research Council (NHMRC) Australia
Awarded by NHMRC Fellowship
The Geelong Osteoporosis Study (GOS) was funded by the National Health and Medical Research Council (NHMRC) Australia (projects 251638, 628582). The funding organisations played no role in the design or conduct of the study, in the collection, management, analysis and interpretation of the data, nor in the preparation, review and approval of the manuscript. MCT was supported by a Deakin Postgraduate Scholarship, KLH-K by an Alfred Deakin Postdoctoral Research Fellowship, NKH by a Deakin Postdoctoral Fellowship and LJW by a NHMRC Fellowship (#1064272).