Journal article

Head Motion During MRI Predicted by out-of-Scanner Sustained Attention Performance in Attention-Deficit/Hyperactivity Disorder

Phoebe Thomson, Katherine A Johnson, Charles B Malpas, Daryl Efron, Emma Sciberras, Timothy J Silk

Journal of Attention Disorders | SAGE PUBLICATIONS INC | Published : 2020


Objective: To characterize head movements in children with ADHD using an ex-Gaussian distribution and examine associations with out-of-scanner sustained attention. Method: Fifty-six children with ADHD and 61 controls aged 9 to 11 years completed the Sustained Attention to Response Task (SART) and resting-state functional magnetic resonance imaging (fMRI). In-scanner head motion was calculated using ex-Gaussian estimates for mu, sigma, and tau in delta variation signal and framewise displacement. Sustained attention was evaluated through omission errors and tau in response time on the SART. Results: Mediation analysis revealed that out-of-scanner attention lapses (omissions during the SART) m..

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Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC

Awarded by NHMRC Career Development Award

Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was funded by the National Health and Medical Research Council of Australia (NHMRC; 1065895, 1008522) and the Collier Foundation, Melbourne, Australia. E.S. was supported by NHMRC Early Career (1037159) and Career Development (1110688) Fellowships. T.J.S. was supported by an NHMRC Career Development Award (1004637). D.E. is supported by a Clinical Scientist Fellowship from the Murdoch Children's Research Institute. The research was also supported by The Royal Children's Hospital, The Royal Children's Hospital Foundation, Department of Pediatrics at the University of Melbourne, Australian Commonwealth Government, and the Victorian Government's Operational Infrastructure Support Program.