Enantiotopic Discrimination by Coordination-Desymmetrized meso-Ligands
Yutang Li, Anna Lidskog, Helena Armengol-Relats, Huong Pham Thanh, Antoine Favraud, Maxime Nicolas, Sami Dawaigher, Zeyun Xiao, Dayou Ma, Emil Lindbaeck, Daniel Strand, Kenneth Waernmark
ChemCatChem | Wiley | Published : 2020
The first examples of enantiopure catalysts that are chiral merely due to coordination of different metal ions at enantiotopic positions of an achiral meso‐ligand are reported. These catalysts exhibit a pseudo‐Cs symmetry and are able to catalyze reactions demanding simultaneous involvement of two catalytic sites. The latter was demonstrated by application in the asymmetric ring‐opening of meso‐epoxides.
We thank the Swedish Research Council, the Royal Physiographic Society of Lund and the Crafoord foundation for grants. We thank Chinese Scholarship Council for PhD scholarship to Yutang Li. We thank the Crafoord foundation for postdoc fellowships to Zeyun Xiao, Dayou Ma, and Emil Lindback.