Journal article

Greater activation of the response inhibition network in females compared to males during stop signal task performance

Alexandra Gaillard, Susan L Rossell, Sean P Carruthers, Philip J Sumner, Patricia T Michie, William Woods, Erica Neill, Andrea Phillipou, Wei Lin Toh, Matthew E Hughes

Behavioural Brain Research | ELSEVIER | Published : 2020

Abstract

Previous neuroimaging studies have reported differences in regional brain activation between males and females during stop signal task performance, suggesting the presence of sex-linked differences in brain network organization of inhibitory ability. Despite a growing literature on sex differences during stop signal task performance, a consensus still has not been reached due to variations in task design and analysis methods. Due to these disparate findings we used up to date stop signal task methods to compare behavioral performance and associated brain activation between males and females using an event-related functional magnetic resonance imaging design. We observed that males were faste..

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Grants

Awarded by National Health and Medical Research Council (NHMRC)


Awarded by NHMRC Senior Research Fellowship


Funding Acknowledgements

The authors acknowledge the facilities and the scientific and technical assistance of the National Imaging Facility (NIF) at the Swinburne University of Technology node. This work was supported by a Project Grant from the National Health and Medical Research Council (NHMRC, GNT1060664). SLR holds an NHMRC Senior Research Fellowship (GNT1154651).