Journal article

Neonatal Tract-Based Spatial Statistics Findings and Outcome in Preterm Infants

BJM van Kooij, LS de Vries, G Ball, IC van Haastert, MJNL Benders, F Groenendaal, SJ Counsell

American Journal of Neuroradiology | AMER SOC NEURORADIOLOGY | Published : 2012

Abstract

BACKGROUND AND PURPOSE: WM injury is associated with different disabilities that children born prematurely may experience during their lives. The aim of this study was to use TBSS to test the hypothesis that WM microstructure at TEA in preterm infants is correlated with cognitive and motor outcome at 2-year corrected age. MATERIALS AND METHODS: Sixty-three preterm infants, born at a mean gestational age of 28.7 weeks, underwent MR imaging and DTI at TEA. Neurodevelopmental performance was assessed by using the BSITD-III. Voxelwise analysis of the DTI data was performed by using TBSS to assess the relationship among FA, AD, and RD at TEA, and cognitive, fine-motor, and gross-motor scores at 2..

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Grants

Awarded by Netherlands Organization for Health Research and Development


Funding Acknowledgements

This work was supported by the Young Investigator Exchange Program Fellowship of the International Pediatric Research Foundation and the Netherlands Organization for Health Research and Development (project 94527022).