Journal article

Pulse transit time as a proxy for vasoconstriction in younger and older adults

Arjen Mol, Carel GM Meskers, Sjoerd P Niehof, Andrea B Maier, Richard JA van Wezel

Experimental Gerontology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020

Abstract

OBJECTIVES: Changes of vasoconstriction may be measured non-invasively using pulse transit time. This study assessed the sensitivity, test-retest reliability (and validity of pulse transit time during vasoconstriction provocation and active standing, and the predictive value of pulse transit time for blood pressure drop. METHODS: Fifty-five younger (age  70 years) underwent electrocardiography, wrist and finger photoplethysmography and continuous blood pressure and total peripheral resistance measurements during vasoconstriction provocation using a cold pressor test (21 younger adults), or active stand tests (all other participants). Pulse transit time was defined as the time lag between the..

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Grants

Awarded by Applied and Engineering Science domain (TTW) of the Netherlands Organization of Scientific Research (NWO): NeuroCIMT-Barocontrol


Funding Acknowledgements

This study was supported by a grant from the Applied and Engineering Science domain (TTW) of the Netherlands Organization of Scientific Research (NWO): NeuroCIMT-Barocontrol (grant no 14901).