Pulse transit time as a proxy for vasoconstriction in younger and older adults
Arjen Mol, Carel GM Meskers, Sjoerd P Niehof, Andrea B Maier, Richard JA van Wezel
Experimental Gerontology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2020
OBJECTIVES: Changes of vasoconstriction may be measured non-invasively using pulse transit time. This study assessed the sensitivity, test-retest reliability (and validity of pulse transit time during vasoconstriction provocation and active standing, and the predictive value of pulse transit time for blood pressure drop. METHODS: Fifty-five younger (age 70 years) underwent electrocardiography, wrist and finger photoplethysmography and continuous blood pressure and total peripheral resistance measurements during vasoconstriction provocation using a cold pressor test (21 younger adults), or active stand tests (all other participants). Pulse transit time was defined as the time lag between the..View full abstract
Awarded by Applied and Engineering Science domain (TTW) of the Netherlands Organization of Scientific Research (NWO): NeuroCIMT-Barocontrol
This study was supported by a grant from the Applied and Engineering Science domain (TTW) of the Netherlands Organization of Scientific Research (NWO): NeuroCIMT-Barocontrol (grant no 14901).