Balancing act: Neural correlates of affect dysregulation in youth depression and substance use - A systematic review of functional neuroimaging studies
Divyangana Rakesh, Nicholas B Allen, Sarah Whittle
Developmental Cognitive Neuroscience | ELSEVIER SCI LTD | Published : 2020
Both depression and substance use problems have their highest incidence during youth (i.e., adolescence and emerging adulthood), and are characterized by emotion regulation deficits. Influential neurodevelopmental theories suggest that alterations in the function of limbic and frontal regions render youth susceptible to these deficits. However, whether depression and substance use in youth are associated with similar alterations in emotion regulation neural circuitry is unknown. In this systematic review we synthesized the results of functional magnetic resonance imaging (fMRI) studies investigating the neural correlates of emotion regulation in youth depression and substance use. Resting-st..View full abstract
Awarded by NHMRC Career Development Fellowship
DR is supported by a Melbourne Research Scholarship. SW is supported by an NHMRC Career Development Fellowship (ID: 1125504). The authors report no potential conflicts of interest.