Journal article

The Impact of Maternal Obesity on Human Milk Macronutrient Composition: A Systematic Review and Meta-Analysis

Gabriela E Leghi, Merryn J Netting, Philippa F Middleton, Mary E Wlodek, Donna T Geddes, Beverly S Muhlhausler

NUTRIENTS | MDPI | Published : 2020


Maternal obesity has been associated with changes in the macronutrient concentration of human milk (HM), which have the potential to promote weight gain and increase the long-term risk of obesity in the infant. This article aimed to provide a synthesis of studies evaluating the effects of maternal overweight and obesity on the concentrations of macronutrients in HM. EMBASE, MEDLINE/PubMed, Cochrane Library, Scopus, Web of Science, and ProQuest databases were searched for relevant articles. Two authors conducted screening, data extraction, and quality assessment independently. A total of 31 studies (5078 lactating women) were included in the qualitative synthesis and nine studies (872 lactati..

View full abstract


Funding Acknowledgements

Gabriela E. Leghi is supported by a FOODplus Early Life Nutrition Scholarship, The University of Adelaide. Donna T. Geddes. is funded by an unrestricted research grant from Medela AG (Switzerland). Beverly S. Mulhlausler. received a Career Development Award from the National Health and Medical Research Council of Australia (NHMRC). The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.