Efficacy of Endoscopic Dilation of Gastroduodenal Crohn's Disease Strictures: A Systematic Review and Meta-Analysis of Individual Patient Data
Dominik Bettenworth, Marcus M Muecke, Rocio Lopez, Amandeep Singh, Weiming Zhu, Feilong Guo, Toshiyuki Matsui, Theodore W James, Hans Herfarth, Martin Goetz, Ren Mao, Satya Kurada, Jochen Hampe, Katja Matthes, John Gasdal Karstensen, Piero V Valli, Marjolijn Duijvestein, Geert D'Haens, Vipul Jairath, Tian Bai Qiu Show all
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | ELSEVIER SCIENCE INC | Published : 2019
BACKGROUND & AIMS: Little is known about the effects of endoscopic balloon dilation (EBD) for strictures of the upper gastrointestinal (UGI) tract in patients with Crohn's disease (CD). We performed a pooled analysis of the efficacy and safety of EBD for UGI CD-associated strictures. METHODS: We searched Embase, Medline, and the Cochrane library, as well as bibliographies of relevant articles, for cohort studies of adults with CD and strictures of the stomach or duodenum (up to the ligament of Treitz) who underwent EBD through December 2016. We obtained data from 7 international referral centers on 94 patients who underwent 141 EBDs. We performed a patient-level meta-analysis of data from pu..View full abstract
Awarded by National Institutes of Health
This work was supported by grants from the National Institutes of Health [T32DK083251, P30DK097948 Pilot, K08DK110415] to F.R.