Journal article

Choroidal Thickness in Young Adults and its Association with Visual Acuity

Samantha SY Lee, Gareth Lingham, David Alonso-Caneiro, Fred K Chen, Seyhan Yazar, Alex W Hewitt, David A Mackey

American Journal of Ophthalmology | ELSEVIER SCIENCE INC | Published : 2020

Abstract

PURPOSE: To describe the choroidal thickness (ChT) in a large sample of young adults with the aim of establishing a normative ChT profile reference in this demographic cohort and explore its association with best-corrected visual acuity (BCVA). DESIGN: Cross-sectional study. METHODS: From a single center, 741 young adults (19-30 years of age, 49% male) were recruited to undergo a comprehensive ophthalmic examination, including BCVA measurement, post-cycloplegic autorefraction, ocular biometry, tonometry, and spectral-domain optical coherence tomography (SD-OCT) imaging. The enhanced depth imaging mode on the SD-OCT was used. The main outcome measure was the central macular ChT (0.5-mm radius..

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)


Awarded by Medical Research Future Fund Career Development Fellowship


Funding Acknowledgements

The eye data collection of the Gen2-20 year follow-up of the Raine Study was funded by Australian National Health and Medical Research Council (NHMRC) (grant 1021105), Ophthalmic Research Institute of Australia (ORIA), Alcon Research Institute, Lions Eye Institute, and the Australian Foundation for the Prevention of Blindness. The core management of the Raine Study is funded by The University of Western Australia, Curtin University, Telethon Kids Institute, Women and Infants Research Foundation, Edith Cowan University, Murdoch University, The University of Notre Dame Australia and the Raine Medical Research Foundation. Dr Lingham is supported by an Australian Government Research Training Stipend. Dr Yazar is supported by aNHMRCEarly Career Fellowship. Dr Chen is supported by Medical Research Future Fund Career Development Fellowship (grant 1142962). Drs Hewitt and Mackey are each supported by a NHMRC Practitioner Fellowship. Financial Disclosures: The authors indicate no financial conflicts of interest. The authors are grateful to the Raine Study participants and their families and we thank the Raine Study and Lions Eye Institute research staff for cohort coordination and data collection.