Journal article

A general moment expansion method for stochastic kinetic models.

Angelique Ale, Paul Kirk, Michael PH Stumpf

The Journal of Chemical Physics | Published : 2013

Abstract

Moment approximation methods are gaining increasing attention for their use in the approximation of the stochastic kinetics of chemical reaction systems. In this paper we derive a general moment expansion method for any type of propensities and which allows expansion up to any number of moments. For some chemical reaction systems, more than two moments are necessary to describe the dynamic properties of the system, which the linear noise approximation is unable to provide. Moreover, also for systems for which the mean does not have a strong dependence on higher order moments, moment approximation methods give information about higher order moments of the underlying probability distribution. ..

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University of Melbourne Researchers

Grants

Awarded by Biotechnology and Biological Sciences Research Council