Journal article
PRIME-HF: Novel Exercise for Older Patients with Heart Failure. A Pilot Randomized Controlled Study
C Giuliano, I Levinger, S Vogrin, CJ Neil, JD Allen
Journal of the American Geriatrics Society | WILEY | Published : 2020
DOI: 10.1111/jgs.16428
Open access
Abstract
OBJECTIVES: To test the hypothesis that (1) older patients with heart failure (HF) can tolerate COMBined moderate-intensity aerobic and resistance training (COMBO), and (2) 4 weeks of Peripheral Remodeling through Intermittent Muscular Exercise (PRIME) before 4 weeks of COMBO will improve aerobic capacity and muscle strength to a greater extent than 8 weeks of COMBO. DESIGN: Prospective randomized parallel open-label blinded end point. SETTING: Single-site Australian metropolitan hospital. PARTICIPANTS: Nineteen adults (72.8 ± 8.4 years of age) with heart failure with reduced ejection fraction (HFrEF). INTERVENTION: Participants were randomized to 4 weeks of PRIME or COMBO (phase 1). All par..
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Funding Acknowledgements
This work was supported by an Australian Government Research Training Program Scholarship for Catherine Giuliano and by the Western Health Research Grant 2016. Shared facilities between Western Health and Victoria University at the Western Centre for Health, Research and Education were used to undertake this project, as well as facilities at the Victoria University Clinical Exercise Rehabilitation Clinic, within the Institute for Health and Sport, Victoria University.