Effect of total arterial grafting in the Arterial Revascularization Trial.
David P Taggart, Mario F Gaudino, Stephen Gerry, Alastair Gray, Belinda Lees, Arnaldo Dimagli, John D Puskas, Vipin Zamvar, Rafał Pawlaczyk, Alistair G Royse, Marcus Flather, Umberto Benedetto, undefined ART investigators
J Thorac Cardiovasc Surg | Published : 2020
OBJECTIVES: The Arterial Revascularization Trial (ART) was designed to compare 10-year survival in bilateral versus single internal thoracic artery grafts. The intention-to-treat analysis has showed comparable outcomes between the 2 groups but an explanatory analysis suggested that those receiving 2 or more arterial grafts had better survival. Whether the exclusive use of arterial grafts provide further benefit is unclear. METHODS: We performed an exploratory analysis of the ART based on conduits actually received (as-treated principle). From ART cohort, only patients receiving at least 3 grafts were included. The final population consisted of 1084, 1010, and 390 patients in the single arter..View full abstract