Journal article

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

Gregory M LaMonte, Frances Rocamora, Danushka S Marapana, Nina F Gnadig, Sabine Ottilie, Madeline R Luth, Tilla S Worgall, Gregory M Goldgof, Roxanne Mohunlal, TR Santha Kumar, Jennifer K Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M Williams, Bing Yu Zou, Andrea L Cheung, Prianka Kumar Show all

Nature Communications | NATURE PUBLISHING GROUP | Published : 2020

University of Melbourne Researchers

Grants

Awarded by Bill and Melinda Gates Foundation


Awarded by National Research Foundation of South Africa


Awarded by Ruth L. Kirschstein Institutional National Research Award from the National Institute for General Medical Sciences


Awarded by Bill & Melinda Gates Foundation


Awarded by NIH


Funding Acknowledgements

We would like to thank the members of the Winzeler lab for technical support, reagents and critical reading of the manuscript. G.L. is supported by an AP Giannini post-doctoral fellowship. S.O. and G.M.G. were funded by the Bill and Melinda Gates Foundation (OPP1054480, and OPP1171497). T.J.E. and R.M. were supported by the National Research Foundation of South Africa (Grant No. 91516). R.M. also acknowledges the University of Cape Town for a travel grant. M.R.L. was supported in part by a Ruth L. Kirschstein Institutional National Research Award from the National Institute for General Medical Sciences (T32 GM008666). M.C.L gratefully acknowledges funding from Wellcome and the Bill and Melinda Gates Foundation. D.A.F. gratefully acknowledges funding from the Medicines for Malaria Venture and the Bill & Melinda Gates Foundation. E.A.W. is supported by grants from the NIH (5R01AI090141 and R01AI103058) and by grants from the Bill & Melinda Gates Foundation (OPP1086217and OPP1141300) as well as by Medicines for Malaria Venture (MMV).