Journal article

Independence of coronary artery disease to subclinical left ventricular dysfunction

Prasanna Venkataraman, Leah Wright, Quan Huynh, Thomas H Marwick

Echocardiography | WILEY | Published : 2020

Abstract

OBJECTIVE: Epicardial atherosclerosis and heart failure while distinct clinical entities share common pathophysiological features including endothelial dysfunction and inflammation. Presence of subclinical disease could lead to early diagnosis and intervention in the other. The aim of our study was to assess the association between coronary calcium score (CCS), conventional cardiovascular risk factors, and echocardiographic markers of subclinical left ventricular dysfunction (S-LVD). METHODS: One hundred and fifty-nine participants aged 40-70 years with intermediate risk of coronary artery disease (5-year risk of 2%-15%) were identified. Computed tomography (CT) CCS and 2-D transthoracic ech..

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