Gram-negative endophthalmitis: A prospective study examining the microbiology, clinical associations and visual outcomes following infection

Abstract

Importance: This is the largest Gram-negative endophthalmitis specific series and provides important evidence to guide management. Background: Endophthalmitis is a sight-threatening emergency. Gram-negative infections are associated with poorer visual outcomes; however, there is limited literature pertaining to this uncommon condition. Design: Prospective case series. Participants: All patients presenting with endophthalmitis to a tertiary institution over a 20-year period. Methods: Data were collected prospectively and entered into a registry. Patients with microbiological evidence of Gram-negative infection were included in the analysis. Main outcomes measures: Final visual acuity (VA), pr..