Journal article
Evidence for subtypes of freezing of gait in Parkinson's disease
KA Ehgoetz Martens, JM Shine, CC Walton, MJ Georgiades, M Gilat, JM Hall, AJ Muller, JYY Szeto, SJG Lewis
Movement Disorders | WILEY | Published : 2018
DOI: 10.1002/mds.27417
Abstract
Background: The purpose of this study is to identify and characterize subtypes of freezing of gait by using a novel questionnaire designed to delineate freezing patterns based on self-reported and behavioral gait assessment. Methods: A total of 41 Parkinson's patients with freezing completed the Characterizing Freezing of Gait questionnaire that identifies situations that exacerbate freezing. This instrument underwent examination for construct validity and internal consistency, after which a data-driven clustering approach was employed to identify distinct patterns amongst individual responses. Behavioral freezing assessments in both dopaminergic states were compared across 3 identified subg..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
K.A.E.M. is supported by a Parkinson Canada Fellowship; J.M.S. is supported by a National Health and Medical Research Council CJ Martin Fellowship (1072403); J.M.H. is supported by a Western Sydney University Postgraduate Research Award; and S.J.G.L. is supported by NHMRC-ARC Dementia Fellowship (1110414). This work was supported by funding to Forefront, a collaborative research group dedicated to the study of non-Alzheimer disease degenerative dementias, from National Health and Medical Research Council of Australia program Grants 1037746 and 1095127. M.G., J.Y.Y.S., C.C.W., and A.A.M. have no funding source to disclose.