Journal article
Predicting the onset of freezing of gait: A longitudinal study
KA Ehgoetz Martens, EL Lukasik, MJ Georgiades, M Gilat, JM Hall, CC Walton, SJG Lewis
Movement Disorders | WILEY | Published : 2018
DOI: 10.1002/mds.27208
Abstract
Background: Freezing of gait is a disabling symptom of Parkinson's disease that ultimately affects approximately 80% of patients, yet very little research has focused on predicting the onset of freezing of gait and tracking the longitudinal progression of symptoms prior to its onset. The objective of the current study was to examine longitudinal data spanning the transition period when patients with PD developed freezing of gait to identify symptoms that may precede freezing and create a prediction model that identifies those “at risk” for developing freezing of gait in the year to follow. Methods: Two hundred and twenty-one patients with PD were divided into 3 groups (88 nonfreezers, 41 tra..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by funding to Forefront, a collaborative research group dedicated to the study of non-Alzheimer's disease degenerative dementias from the National Health and Medical Research Council of Australia program granst 1037746 and #1095127. Kaylena A. Ehgoetz Martens is supported by a Parkinson Canada Postdoctoral fellowship. Matthew J. Georgiades is supported by the Sydney Medical School RA Money Postgraduate Research Scholarship in Neuroscience. Moran Gilat is supported by a University of Sydney International Scholarship. Julie M. Hall is supported by a Western Sydney University Postgraduate Research Award. These funding organizations did not play any role in the design and conductor of the study; collection, management, analysis or interpretation of the data; nor the preparation, review, approval of the manuscript, or decision to submit the manuscript for publication.