Journal article

Do Age at Diagnosis, Tumour Thickness and Tumour Site Explain Sex Differences in Melanoma Survival? A Sequential Causal Mediation Analysis Using Cancer Registry Data

N Afshar, SG Dashti, V Thursfield, H Farrugia, GG Giles, RL Milne, DR English

Journal of Global Oncology | American Society of Clinical Oncology (ASCO) | Published : 2018

Abstract

Background: Previous research has shown that women diagnosed with melanoma have better survival than their male counterparts, but little is known about the underlying mechanisms by which sex affects melanoma survival. Aim: The aim of this study was to quantify the contribution of age at diagnosis, tumor thickness and tumor site to sex differences in 1-year and 5-year melanoma-specific survival. Methods: We conducted a population-based study using cancer registry data including 6,009 men and 5,232 women aged 15-70 years with first primary melanoma diagnosed between 2007 and 2015 in Victoria, Australia. We excluded cases notified via death certificate only. Deaths to the end of 2015 were ident..

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