Radiation-Associated Thyroid Cancer Surveillance and Management in a Cohort of Late Effects Patients

Abstract

Background and aims: Compared to the general population, the incidence of thyroid cancer in childhood and adolescent and young adult malignancy survivors is increased 14.0–18.0 times (CI 11.7–23.8). The cumulative incidence is variably reported as 0.5% by age 45 with 30-year incidence of 1.3% in women and 0.6% in men. This study aims to evaluate the incidence of radiation-associated thyroid cancer amongst patients treated with prior radiation to the thyroid followed up in a late effects service. A secondary aim was to assess screening compliance in this cohort. Methods: The medical records of all patients attending the late effects service from 1 January 2000 to 20 February 2013 were interro..