Journal article

The Association Between Muscle Mass and Strength in Relation to Bone Measures in a Paediatric Population: Sex-Specific Effects

Natalie K Hyde, Rachel L Duckham, John D Wark, Sharon L Brennan-Olsen, Sarah M Hosking, Kara L Holloway-Kew, Julie A Pasco

Calcified Tissue International | SPRINGER | Published : 2020


Post-puberty, bone mass displays clear sex-specific patterns. However, research has suggested that a sexual dimorphism in bone mass is evident in younger children and is likely attributable to differences in lean mass. Thus, we aimed to determine whether the association with both overall muscle mass and/or muscle strength was different between the sexes in a paediatric population. Participants were recruited as part of the Vitamin D in Pregnancy Study, Australia. There were 209/402 (52.3%) children at the 11-year follow-up, and 172 had complete data. Children were assessed for bone mineral content (BMC), bone mineral density (BMD) and lean mass by DXA (Lunar). Handgrip strength (kg) was meas..

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Funding Acknowledgements

The authors wish to thank the staff and participants of the Vitamin D in Pregnancy Study. The project has received funding from the National Health and Medical Research Council and the Bupa Health Foundation. NKH and JAP are the current recipients of an unrelated grant from the Norman Beischer Medical Research Foundation. SMH and JAP are currently receiving unrelated project funding from Amgen. JAP is also an investigator on an unrelated National Health and Medical Research Council grant.